ZRSR2 and myocardial infarction: In the first patient (male ET) who suffered from myocardial infarction at follow-up, we detected ZRSR2 p.Ser447_Arg448dup c.1338_1343dup variant at high VAF (ranging 84,78% - 84,38% between samples), which is suspected to increase the risk of thrombosis.