This process enhances extracellular matrix (ECM) interaction and DNA repair regulation, thereby promoting NSCLC survival and progression(Constanzo et al. 2016).The Slug-E-cadherin axis has emerged as a critical regulatory pathway in NSCLCs, whereby the anomalous overexpression of Slug facilitates the metastasis of cancer. The gene discussed is SNAI2; the disease is non-small cell lung carcinoma.