APOE and memory impairment: It reached moderate severity level years later hippocampus atrophy and even after memory impairment in the profile APOE4 non carriers and low education while the degradation of A\documentclass[12pt]{minimal}\usepackage{amsmath}\usepackage{wasysym}\usepackage{amsfonts}\usepackage{amssymb}\usepackage{amsbsy}\usepackage{mathrsfs}\usepackage{upgreek}\setlength{\oddsidemargin}{-69pt}\begin{document}$$\beta$$\end{document}β42 marker was at about the same time as the one of hippocampus atrophy for APOE4 carriers.