HTT and amyloidosis: In addition, there are a number of amyloidosis-related disease states which primarily involve intracellular accumulation of amyloid aggregates, such as Alzheimer’s related tau amyloidosis (Nizynski et al. 2017), Parkinson’s disease-related α-synuclein amyloid formation (Lücking 2000) and Huntington’s disease-related huntingtin amyloid formation (Ross and Tabrizi 2011).