HMGCS2 and clear cell renal carcinoma: Following the study by Wang et al. (32457595), we performed HMGCS2 knockdown in renal clear cell carcinoma cell lines (OSRC2 (Fig. 8A), 786-O (Fig. 8B), A498 (Fig. 8C)), as well as in normal human proximal tubule cells (Fig. 8D).