CircCARM1 interacts with miR-1252-5p in vitro and negatively correlates with miR-1252-5p in BC tissues, and expression of circCARM1 promotes the upregulation of glycolytic enzyme 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 (PFKFB2) through miR-1252-5p sequestration [144]. Here, PFKFB2 is linked to breast cancer.