Using the morphomolecular approach for the diagnosis of MLA of the female genital tract [mixed morphology on H&E-staining and immunoexpression of mesonephric-like markers; see above, (Horn et al. 2020; Pors et al. 2021; McCluggage et al. 2022)], it has been shown that a KRAS-mutation is a common finding in MLA (Mirkovic et al. 2018; Kolin et al. 2019; Horn et al. 2020; Ma et al. 2022; da Silva et al. 2021; Koh et al. 2022; Deolet et al. 2022; McCluggage et al. 2020). The gene discussed is KRAS; the disease is microphthalmia with limb anomalies.