Six families of cysteine proteases include Ub-specific proteases (USPs), Ub C-terminal hydrolases (UCHs), ovarian tumour proteases (OTUs), Machado-Josephin domain-containing proteases (MJDs), MIU-containing novel DUB (MINDY), and zinc finger with UFM1-specific peptidase domain protein/C6orf113/ZUP1 (ZUFSP), are among the six subfamilies (cysteine-dependent proteases). This evidence concerns the gene ZUP1 and ovarian neoplasm.