PLA2R1 and Hepatic fibrosis: Expression of Col1a1, a major component of collagen, and of Tgfb1 an important promoter of fibrosis (Kim et al., 2018; Walton et al., 2017) was also stronger following administration of the WD in WT mice compared with Pla2r1 KO mice (Figure S5B,C), further supporting that Pla2r1 KO mice were protected from liver fibrosis.