The results showed that the tumor growth speed in ERCC6L+/+ PyMT mice was significantly faster than that in mice with the ERCC6L deletion, and there was also a statistically significant difference in the tumor growth rate between ERCC6L+/− PyMT (P = 0.002) and ERCC6L−/− PyMT mice (P = 0.0016) without a significant change in body weight (Fig. 5C-D). The gene discussed is ERCC6L; the disease is neoplasm.