Besides, studies have shown that MIAT is upregulated in periodontitis tissues and can promote inflammation by regulating the expression of pro-inflammatory cytokines, such as IL-6 and TNF-α, through the NF-κB signaling pathway, which suggests that MIAT/ NF-κB pathway may become a new target for periodontitis treatment [38, 56].Therefore, the 10 core periodontitis-associated necroptosis lncRNAs selected through bioinformatics techniques in this study have certain clinical significance and can provide new references for the diagnosis and treatment of periodontitis. Here, MIAT is linked to periodontitis.