The Wilcoxon analysis of the expression levels of 10-lncRNAs in the healthy and periodontitis samples revealed that CARMN, FAM30A, LINC00582, MIAT, OSER1-DT, PCOLCE-AS1 and RNF144A-AS1 were upregulated in periodontitis (Fig. 8A and B), while EPB41L4A-AS1, LINC01004, and MALAT1 were downregulated in periodontitis (Fig. 8C). The gene discussed is PCOLCE; the disease is periodontitis.