HSPA4 and periodontitis: Figure 2B and Additional file 5 showed the volcano plots of differentially expressed genes (DEGs) in the GSE16134 dataset and seven necroptosis-related differentially expressed genes (7-DEGs) (ATRX, HSPA4, ZBP1, MLKL, BNIP3, TNFRSF1B, SLC39A7) in periodontitis were identified.