BRAF and neoplasm: In addition, when we assessed genetic mutations stratified by tumor location, RAS mutations were more frequently detected in solitary CRC for both right-sided (56.6% vs. 6.3%, p < 0.001) and left-sided (52.2% vs. 21.4%, p = 0.026) tumors, whereas no differences were found for MSI status or BRAF mutations.