Furthermore, we conducted assessment of the correlation between plasma SOST and AD biomarkers including Aβ40, Aβ42, Aβ42/Aβ40 ratio, NFL, GFAP, t-tau, p-tau181 and p-tau231, as well as parallel comparisons of the diagnostic accuracy of plasma SOST with these blood biomarkers. Here, GFAP is linked to Alzheimer disease.