Tumor-promoting CAFs subsets include Inflammatory CAFs (iCAFs), Zinc finger E-box binding homeobox 1 (Zeb1)+CAFs, leucine-rich replication 15+ (LRRC15+) CAFs, Serum amyloid A3+CAFs (SAA3+CAFs), FAP+/CXCL12+CAFs, CD10+/GPR77+CAFs, CD105+CAFs, Hypoxia+CAFs, Metabolic CAFs, Antigen-presenting CAFs (apCAFs) [29]. The gene discussed is MME; the disease is neoplasm.