IDH2 and central nervous system cancer: In line with the literature,3,27 patients with glioblastoma, IDH-wildtype were the oldest, followed in descending order of age by oligodendroglioma, IDH-mutant and 1p/19q codeleted, astrocytoma, IDH-mutant, and the remaining other gliomas (including BRAF mutant lesions characteristic of children and young adults).