MGMT and glioblastoma: For example, two distinct communities, Blocks 1 and 6, with the same diagnosis—glioblastoma, IDH-wildtype—yielded rather different hazard ratios: 2.76 versus 2.27, the former more likely to exhibit MGMT methylation and high EGFR amplification than the latter (Fig. 6 and Supplementary Fig. 9).