GPC3 and neoplasm: For instance, Dong et al. screened an APS613-1 aptamer to specifically bind to the GPC3 protein by capillary electrophoresis-SELEX technology [24, 25]; Yang et al. verified that aptamers could be anchored on the surface of immune cells to endow immune effector cells with tumor specific targeting properties [20]; Zhang et al. equipped NK cells with TLS11a and PD-L1 aptamers to enhance adoptive immunotherapy in solid tumor [26].