Boaro et al. reports IDH (isocitrate dehydrogenase) mutation, a favourable prognostic indicator to be lower (3.8%) in bGBM than GBM (5–12%), as well as bGBM having lower MGMT (O6-methylguanine-DNA-methyltransferase) methylation rates than GBM, although the latter was not significant [4, 6]. Here, MGMT is linked to glioblastoma.