DNMBP and early-onset autosomal dominant Alzheimer disease: For instance, TubA and the shRNA of HDAC6 can ameliorate neuronal necroptosis from oxygen–glucose deprivation/reperfusion (OGDR),15, 25 alleviate cognitive dysfunction in mice with Alzheimer's disease (AD),17 and prevent axonal loss in mice with Charcot–Marie‐Tooth disease.26