STAT1 and osteoporosis: In addition, although there was no significant difference in the NE/Ovx group, the level of Stat1 in the RE/Ovx group was significantly higher than that in the NE/Ovx group, suggesting that although Stat1 may not play an important role in ovariectomized osteoporosis, it may be involved in the above-mentioned mechanism of resistance exercise, which needs to be further explored in the following study.