KEGG enrichment analysis revealed that the antihypertensive mechanism of Ilex kudingcha was mainly concentrated in lipid and atherosclerosis, fluid shear stress and atherosclerosis, the AGE-RAGE signaling pathway in diabetic complications, human cytomegalovirus infection, the TNF signaling pathway, chemical carcinogenesis receptor activation, hepatitis B, prostate cancer, and Chagas disease (Figure 7). The gene discussed is TNF; the disease is atherosclerosis.