ANGPT2 and acute respiratory distress syndrome: Angiopoietin-2 (Ang-2), a lung endothelial marker aided in the determination of ARDS severity and mortality, improved the ability of the Lung Injury Prediction score (area under-ROC = 0.84, p = 0.05) and augmented clinical scores by identifying patients who were developing or at high risk of lung injury during treatment [1, 21].