Further, seven LD blocks (r2 > 0.6) localized to LSP1 have been associated with BrCa incidence or outcome, including 5 LD blocks that correlated with altered LSP1 expression in leukocytes and 29 out of 78 SNPs (37%) within the LD blocks that were predicted to alter a functional motif (Table S17). The gene discussed is LSP1; the disease is invasive breast carcinoma.