LSP1 was also distinct from other iTME candidates in that it has been associated with BrCa outcome29 in addition to incidence of BrCa6,24,25,26,27 and autoimmunity,31,35,53,54 suggesting that LSP1 is a germline iTME modifier of BrCa incidence and disease progression. This evidence concerns the gene LSP1 and Autoimmunity.