Fos is part of the activating protein-1 (AP-1) transcription factor complex and FOS has roles in oncogenic processes such as tumor growth and progression, as well as biological processes like proliferation, differentiation, epithelial-to-mesenchymal transition and apoptosis (Wagner, 2002; Milde-Langosch, 2005; Durchdewald et al., 2009; Velazquez et al., 2015; Chen et al., 2017; Rodriguez-Berdini et al., 2020). Here, JUN is linked to neoplasm.