INS and Crohn disease: - Foliates produced by Lactobacillus helveticus CD6 can ameliorate DNA synthesis and repair and offer antioxidants.  - Supplementation of Lactobacillus acidophilus in yogurt was associated with higher vitamin B12 levels which are low in Crohn's disease [23] - Microbiota can metabolize polyphenols and secrete urolithin A, equol, and 8-prenylnaringenin (8-PN), ameliorating sugar and fatty acid metabolism and enhancing insulin sensitivity.