The univariate analysis showed significant associations with serum Na levels in the following parameters: sex, etiology (alcoholic liver disease), total bilirubin, aspartate aminotransferase (AST), alanine aminotransferase (ALP), γ-glutamyl transpeptidase (γ-GTP, albumin, total cholesterol, blood urea nitrogen (BUN), creatinine, prothrombin activity, NLR, CRP, LS, HCC, ascites, diuretic use, and ALBI score (p < 0. This evidence concerns the gene ALB and hepatocellular carcinoma.