ALBI, albumin–bilirubin grade; ALP, alkaline phosphatase; ALT, alanine aminotransferase; AST, aspartate aminotransferase; BMI, body mass index; BUN, blood urea nitrogen; CONUT, controlling nutritional status; CRP, C-reactive protein; γ-GTP, γ-glutamyl transpeptidase; HCC, hepatocellular carcinoma; NLR, neutrophil-to-lymphocyte ratio; PT, prothrombin activity; TC, total cholesterol. The gene discussed is F2; the disease is hepatocellular carcinoma.