CRP and infection: After a thorough examination of clinical symptoms, signs (such as increased body temperature, decreased blood pressure, increased heart rate or increased respiratory rate, etc.), laboratory results (white blood cell count, neutrophil count, procalcitonin and C-reactive protein, etc.), imaging results, treatment choices, and outcomes, three skilled doctors made the infection diagnosis (Horan et al., 2008; Cui et al., 2022, 2010–2019).