The most frequently mutated genes were TET2 (58/128 total cases, 45%; and 57/116 T-cell lymphoma cases, 49%), RHOA (24/116, 21%), DNMT3A (20/116, 17%), TP53 (13/116, 11%) and JAK1 (11/128 total cases, 9%; and 10/116 T-cell lymphoma cases, 9%) (Figure 1C). The gene discussed is JAK1; the disease is T-cell non-Hodgkin lymphoma.