CRLF2 and acute lymphoblastic leukemia: The same was true for losses of CDKN2A and CDKN2B. Deletions in RB1, EBF1, ETV6, ERG (Supplementary Figure 2C), and BTG1 were identified in isolated cases, whereas CNAs in the PAR1 region (Supplementary Figure 2D), which resulted in the juxtaposition of P2RY8 and CRLF2, were only observed among B-other ALL and DS-ALL.