The prevalence of retinopathy was 36.4%; of them, 57.5% were mild, 19.9% were moderate, 11% were severe NP, and 11.6% were PR. The rate of maculopathy was 7.2%. Risk factors of DR included older age, early onset, longer duration of diabetes, poor glycemic control, insulin use, and the presence of hypertension, diabetic neuropathy, or nephropathy. This evidence concerns the gene INS and Hypertension.