TSPO and breast carcinoma: Our observations also showed that the increase in ROSis blocked by the pharmacological inhibition of TSPO, confirming thestudies in mammary carcinoma and cardiomyocyte cell lines using geneticinhibition of TSPO.40,46 This ROS stimulation effect isalso obtained by the overexpression of TSPO, apart from the presenceof pro-inflammatory stimulation.