The overexpression of stanniocalcin-1 (STC1) in tumor cells inhibits the expression of monocyte chemokine receptors chemokine CCR2, CCR4, and colony-stimulating factor 1 receptor (CSF1R), thereby suppressing the recruitment of monocytes to the TME (Leung and Wong, 2020). The gene discussed is STC1; the disease is neoplasm.