SOAT1 and esophageal cancer: In esophageal cancer Eca109 cells (Feng et al., 2021), Naringin can upregulate the expression levels of BAX, Cytochrome c oxidase (CytC), caspase-3 and -9, downregulate the expression of Bcl2, inhibit the JAK/STAT signaling pathway, and promote the apoptosis of Eca109 cells.