Naringin can inhibit the invasion and migration of colorectal cancer cells HCT116 and LOVO by inhibiting miR-216a and regulating the expression of CEMIP protein below its direct target KIAA1199 (Zhang et al., 2017); It can promote the expression of E-cadherin and reduce N-cadherin by regulating the miR-628-5p pathway, thereby blocking EMT and inhibiting the invasion and metastasis of cervical cancer ME-180 cells (Rui-ying et al., 2022). Here, CEMIP is linked to cervical cancer.