PTGS2 and cervical carcinoma: Zeng et al. (Zeng et al., 2014) confirmed that Naringin inhibits NF- κ Activation of B/COX-2-caspase-1 pathway and downregulation of NF- κ The expression of Bp65, COX-2 and Cysteine protease 1 (caspase-1) upregulates the expression of cleaved caspase-3, thus inducing death receptor mediated apoptosis of cervical cancer HeLa cells.