ELOVL5 and peripheral neuropathy: Furthermore, ELOVL5 is highly expressed in the central nervous system and mutations in the gene were found to be the cause of spinocerebellar ataxia type 38 (SCA38), a rare autosomal neurological disease characterized by gait abnormality, dysarthria, dysphagia, hyposmia, and peripheral neuropathy (Balbo et al., 2021).