Previous studies have shown that ADAR1p150 promotes the maturation of miRNA-222 by forming a complex with Dicer enzyme, thereby playing a role in regulating the expression of phosphatase and tensin homolog (PTEN), ultimately producing an anti-apoptotic effect on cardiomyocytes and participating in the pathophysiological process of viral myocarditis (Zhang et al., 2019). The gene discussed is PTEN; the disease is viral myocarditis.