There are many divisions of cytokines and tumor necrosis factor-α (TNFα), interleukin-6 (IL-6), and interleukin-1 (IL-1) belong to pro-inflammatory cytokines [3] and these cytokines are disturbed in various patients, in COVID-19 as well as in cancer and they represent negative prognostic markers or the inflammation [4, 5]. The gene discussed is TNF; the disease is cancer.