The unidentified rumen bacterium RNF82, the bacterial biomarkers in the mastitis group, were negatively correlated with cotinine N-oxide, and Corey PG-lactone diol (p < 0.05) and positively correlated with 2-amino-octadecanoic acid, erucamide, and ethosuximide M7 (Figure 4C). Here, TRIM24 is linked to mastitis.