IL33 and systemic inflammatory response syndrome: For example, in the abovementioned study of 14 polytrauma patients, plasma IL-33 levels at hospital admission were reported to be positively associated with SIRS and Denver MOF scores at day 3 post-injury (164), whereas non-survivors of blunt trauma presented with significantly lower IL-33 concentrations 24-72 hours post-injury when compared to survivors (166).