Based on the results of enrichment analysis, DEGs were mainly enriched in biological functions such as immune response, regulation of immune system process, defense response and leukocyte activation, and pathways associated with immunity and cancer-related signaling pathways, including the PI3K-Akt signaling pathway, P53 pathway, IL2-STAT5 signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, and B-cell receptor signaling pathway. This evidence concerns the gene CD274 and cancer.