Among the three isoforms (KRAS, NRAS, and HRAS), Kirsten rat sarcoma viral oncogene homolog (KRAS) is the common oncogene in a large percentage of cancers, including pancreatic cancer, non-small cell lung cancer (NSCLC), and colorectal cancer (3–6). The gene discussed is KRAS; the disease is familial pancreatic carcinoma.