MTOR and asthma: Based on the results of the CCK-8, EdU, Transwell, and Fluo-3AM assays, an AMPK/mTOR inhibitor inhibited the ectopic expression of Sestrin2 and an AMPK/mTOR activator attenuated the cellular function of silenced Sestrin2, including the viability, proliferation, migration, and calcium flow, in ASMCs in the asthma group (Figure 6A–6D).