This increases the sensitivity of carcinogenic factors.[50, 51, 52] Studies have shown that in the face of negative life events for regional breast cancer after surgical treatment, stress levels significantly reduced NK cell lysis, NK cell response to recombinant interferon gamma (IFN-γ), and peripheral blood lymphocyte proliferation response to phytoagglutinin and monoclonal antibodies against T-cell receptors. The gene discussed is IFNG; the disease is breast carcinoma.