The SHOX gene is also associated with skeletal defects such as Léri-Weill dyschondrosteosis (Benito-Sanz et al., 2012), short stature, and limb deformities in humans (Jorge et al., 2007; Chen, Wildhardt, et al., 2009; Raudsepp et al., 2012). This evidence concerns the gene SHOX and Leri-Weill dyschondrosteosis.