SLC6A1 and neurodevelopmental disorder: Although seizures may have been the primary focus of research in SLC6A1-NDD, behavioral issues are not to be underestimated, as it is well-known that, e.g., ASD contributes to high levels of stress in parents, and may lead to a poorer quality of life in both the patient and the family especially if co-occurring with a neurodevelopmental disorder (Lach et al., 2009; Purpura et al., 2021).