Thus, the Fanconi-like phenotype of p53Δ31/Δ31 cells most likely results from a decreased expression of not only Fanca, but also additional p53-DREAM targets mutated in Fanconi anemia such as Fancb, Fancd2, Fanci, Brip1, Rad51, Palb2, Ube2t or Xrcc2, for which functional or putative DBSs were also found with our systematic approach. The gene discussed is PALB2; the disease is Fanconi anemia.