And compared with normal tissues, BIRC5 expression is significantly higher in tumor tissues samples from patients with 20 out of 33 tumor types, including bladder urothelial carcinoma (BLCA), BRCA, HNSC, lung adenocarcinoma(LUAD), lung squamous cell carcinoma (LUSC) and READ (Fig. 1B). This evidence concerns the gene BIRC5 and bladder transitional cell carcinoma.