Single cell analysis has indicated that only a specific subpopulation of cancer fibroblasts express IL-6, and in pancreatic cancer this IL-6 sub-population was found to be mutually exclusive from α-Smooth Muscle Actin-expressing fibroblasts [47,51], which is consistent with our data suggesting that the cultured keloid fibroblasts are not myofibroblasts. This evidence concerns the gene IL6 and pancreatic neoplasm.