The association of these non-synonymous alterations with MDS and AML has rarely been reported, except for BCOR. Most genes identified in the gene expression profiles from RNA-seq of FUS-ERG Ba/F3 cells did not have non-synonymous alterations in the WGS of patients with MDS transformed to AML, except for LAT2. LAT2 was downregulated in RNA-seq. The gene discussed is ERG; the disease is myelodysplastic syndrome.