Correlation analysis revealed strong linear associations between BCL2L13 and important autophagy-related genes, including MAP1LC3B, BECN1, ATG3, ATG4B, ATG7, ATG9A (Fig. 3E), ULK1, ATG2A, ATG2B, ATG5, ATG12, and BNIP3 (Supplementary Fig. S1) in GBM from TCGA database, highly suggesting that BCL2L13 mediates autophagy in GBM. The gene discussed is BCL2L13; the disease is glioblastoma.