To further elucidate the role of BCL2L13 in the development of GBM, an orthotopic mouse model was established with luciferase-stable GBM#P3 cells transduced with sh-NC (n = 6) or sh-BCL2L13#3 (n = 6), and tumor growth was examined over time using bioluminescence values. The gene discussed is BCL2L13; the disease is glioblastoma.