PRKCSH and renal cell carcinoma: Specifically, this study focused on and discussed the action of circCOL5A1 in controlling glycolysis of RCC cells, and the collected data presented that circCOL5A1, as a novel oncogene, encourages the malignant behavior of RCC by promoting cellular glycolysis, which is potentially related to the axis of miR-370-5p/PRKCSH.