Compared with the control group, the levels of estradiol (E2), testosterone (T), luteinizing hormone (LH) and the rate of luteinizing hormone/follicle stimulating hormone (LH/FSH) in PCOS group were significantly increased, while the level of progesterone (P) was significantly reduced (Supplementary Table 1). This evidence concerns the gene PLOD1 and polycystic ovary syndrome.